Arthritis is a term used to describe various inflammatory joint disorders, each with its unique characteristics and underlying causes. Two of the most prevalent types are osteoarthritis (OA) and rheumatoid arthritis (RA). While they share the common symptom of joint pain, they differ significantly in terms of causes, risk factors, and treatment approaches. In this blog, we’ll delve into the distinctions and resemblances between osteoarthritis and rheumatoid arthritis to help you better understand these conditions.

Osteoarthritis (OA)

  • Causes: Osteoarthritis is primarily a degenerative joint disease caused by the gradual breakdown of joint cartilage. Wear and tear on the joints over time, aging, and joint injuries are common contributors.
  • Prevalence: OA is more prevalent and often associated with older age. It typically affects weight-bearing joints like knees, hips, and the spine.
  • Inflammation: While inflammation can occur in OA, it is not the central feature of the condition. Inflammatory responses are usually localized to the affected joint.
  • Symptoms: Symptoms include joint pain, stiffness, and reduced range of motion. Pain tends to worsen with activity and improve with rest.
  • Treatment: OA management focuses on pain relief and preserving joint function. Treatments may include physical therapy, pain medications, lifestyle modifications, and joint injections.

Rheumatoid Arthritis (RA)

  • Causes: Rheumatoid arthritis is an autoimmune disorder where the body’s immune system mistakenly attacks the synovium (the lining of the membranes that surround the joints). The exact cause is unknown.
  • Prevalence: RA can affect individuals of any age, including young adults. It typically affects multiple joints, including smaller joints like those in the hands and feet.
  • Inflammation: Inflammation is a hallmark of RA. It can lead to systemic effects, affecting not only joints but also other organs and systems in the body.
  • Symptoms: RA symptoms include joint pain, swelling, morning stiffness, fatigue, and general malaise. Symptoms often occur symmetrically (affecting both sides of the body).
  • Treatment: RA management aims to reduce inflammation, control symptoms, and prevent joint damage. Medications, including disease-modifying antirheumatic drugs (DMARDs), biologics, and lifestyle changes, are typically part of the treatment plan.

Key Differences and Similarities

  • Underlying Cause: The fundamental difference is that OA is degenerative, while RA is autoimmune. OA results from wear and tear on the joints, while RA is driven by an overactive immune response.
  • Age of Onset: OA is more common in older individuals, whereas RA can affect people of all ages.
  • Inflammation: Inflammation is a central feature of RA but not OA. RA can lead to systemic health issues, while OA generally remains localized.
  • Joint Involvement: OA often affects weight-bearing joints and tends to be localized, whereas RA can affect multiple joints and is typically symmetrical.
  • Treatment Approach: Treatment for OA primarily focuses on pain relief and lifestyle modifications, while RA treatment aims to control inflammation and may involve more aggressive medications.


Osteoarthritis and rheumatoid arthritis may both cause joint pain, but their underlying causes, age of onset, patterns of joint involvement, and treatment approaches differ significantly. Understanding these distinctions is essential for accurate diagnosis and effective management. If you suspect you have either condition or are experiencing joint pain, consult a healthcare professional for a proper evaluation and personalized treatment plan.

Remember, early diagnosis and appropriate treatment can make a substantial difference in managing both osteoarthritis and rheumatoid arthritis, allowing individuals to lead active and fulfilling lives despite their joint conditions.

Expert Care and Hope for Better Joint Health at iSCORE

If you or a loved one is living with osteoarthritis and seeking expert care, you’re in capable hands with Drs. Maxim Moradian and Revik Vartanian at iSCORE. With their wealth of experience and dedication to your well-being, they offer hope for better joint health and enhanced quality of life.

Don’t let osteoarthritis hold you back from the activities you love. Reach out to Drs. Moradian and Vartanian today to explore the comprehensive services and personalized care they provide. Whether you’re looking for innovative treatments, pain management strategies, or simply guidance on managing your osteoarthritis, they’re here to support you on your journey to optimal joint health.

Contact their offices at (818) 338-6860 or (626) 460-1096, or visit their website to learn more about their expertise in osteoarthritis care and schedule an appointment. Your path to better joint health starts here, with a team committed to your well-being.